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Elisha 时间: 05-17 17:42   主题:无标题
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For example the heterologous promoter can be inducible such that transcription of all or part of the viral genome will occur only when the induction factors are present.
Examples of heterologous promoters which can be used include for example viral simian virus 40 (SV40) (e.g. early or late) cytomegalovirus (CMV) (e.g. immediate early) Moloney murine leukemia virus (MoMLV) Rous sarcoma virus (RSV) and herpes simplex virus (HSV) (thymidine kinase) promoters.
Examples of RNA export elements include but are not limited to the human immunodeficiency virus (HIV) rev response element (RRE) (see e.g. Cullen et al. 1991. J. Virol. Generally the RNA export element is placed within the 3\‘ UTR of a gene and can be inserted as one or multiple copies.
The term "export element" refers to a cis-acting post-transcriptional regulatory element which regulates the transport of an RNA transcript from the nucleus to the cytoplasm of a cell. In particular embodiments vectors of the invention lack or do not compr
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