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Signal transducer and activator of transcription 1 (STAT1) is an important intracellular signalling pathway that is crucial for the growth and development of cells. Tumour necrosis factor α inducible protein 6 (TSG-6) is a secreted protein that binds to integrin α2β1 and its receptor CD44 and regulates cell proliferation and angiogenesis. However it is unclear whether TSG-6 can promote the proliferation of gastric cancer cells and gastric cancer cell progression through STAT1. In this study we examined the role of TSG-6 in the proliferation of gastric cancer cells and gastric cancer cell progression. We found that TSG-6 significantly promoted the proliferation of SGC7901 and MKN45 cells a
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